In 2025, the Nobel Prize in Physiology or Medicine was awarded in Stockholm to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for pioneering discoveries of peripheral immune tolerance.
Winners of the 2025 Nobel Prize in Medicine
Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi received the 2025 Nobel Prize in Physiology or Medicine for discoveries that elucidate peripheral immune tolerance.
Scientific Impact
Their work initiated a new research area and accelerated development of therapies for cancers and autoimmune diseases.
Prize Value and Awards
Each laureate will receive 11 million Swedish crowns, amounting to over 4.2 million Polish zlotys, along with a gold Nobel medal and a calligraphed diploma.
History and Eligibility of the Nobel Prize in Medicine
The award, one of five founded by Alfred Nobel, has been administered by the Nobel Foundation and awarded by a committee elected by the Karolinska Institute. The first laureate was Emil Adolf von Behring for his serum therapy work against diphtheria.
Selection Process and Nobel Week
The announcement of medicine and physiology laureates usually starts Nobel Week, during which additional events and announcements take place.
