A hantavirus outbreak aboard the MV Hondius, currently anchored off Cape Verde, has resulted in three fatalities and is hindering medical evacuations.
Cruise Ship Hantavirus Outbreak Confirmed
Three people have died and one is in critical condition following a hantavirus outbreak on the MV Hondius cruise ship. Five additional cases are currently under observation as suspected infections.
The World Health Organization (WHO) has launched an epidemiological investigation and is coordinating medical evacuations of patients from the ship.
Voyage Origin and Route
The MV Hondius departed Ushuaia, Argentina, on March 20th, intending to travel through Antarctica, the Falkland Islands, South Georgia, Nightingale Island, Tristan da Cunha, Saint Helena, and Ascension Island, concluding in Cape Verde on May 4th. The ship carried approximately 150 passengers and 71 crew members, including one onboard doctor.
The 107.6-meter Dutch-flagged polar-class vessel is operated by Oceanwide Expeditions, a company specializing in expedition cruises.
Initial Cases and Fatalities
The first symptoms appeared in a 70-year-old Dutch citizen who developed a severe respiratory infection and died onboard. His body was transported to Saint Helena, a British Overseas Territory in the South Atlantic.
His 69-year-old wife subsequently fell ill, was evacuated to South Africa, and died in a Johannesburg hospital while attempting to return to the Netherlands. Two Dutch citizens are among the three confirmed deaths.
Laboratory Confirmation and Current Status
Hantavirus has been laboratory-confirmed in one patient. A 69-year-old British citizen is currently in intensive care in Johannesburg with a confirmed hantavirus infection, representing the only clinical confirmation to date. The remaining five suspected cases are still under investigation.
South Africa’s Ministry of Health, through spokesperson Foster Mohale, confirmed the test results to AFP.
WHO Assessment and Evacuation Delays
In a statement on X (formerly Twitter), the WHO reported that of six individuals exhibiting symptoms, three have died, one is in intensive care, and two crew members still onboard require urgent medical attention. Local health personnel have assessed their condition, but authorities in Cape Verde had not authorized any of the sick to disembark as of 11:00 PM Central European Time on Sunday.
Transmission and Viral Strain
Hantavirus belongs to the Bunyaviridae family and naturally occurs in wild rodents. Transmission to humans primarily occurs through inhalation of air contaminated with rodent droppings, urine, or saliva, and less frequently through direct contact with contaminated surfaces. Human-to-human transmission is rare but not impossible, a factor of particular concern to the WHO.
Infection manifests differently depending on the strain. Hemorrhagic fever with renal syndrome is prevalent in Europe and Asia, while hantavirus pulmonary syndrome dominates in the Americas, with a mortality rate exceeding one-third of patients in the United States, according to the Centers for Disease Control and Prevention.
There is no specific antiviral treatment; therapy focuses solely on supportive care.
Expert Commentary and Origin Investigation
Scott Miscovich, a family physician and president of Premier Medical Group, told CNN that a hantavirus outbreak on a ship that did not port in endemic regions is unusual. The Ministry of Health of the Argentinian province of Tierra del Fuego, where Ushuaia is located, stated that no confirmed cases of hantavirus infection have ever been recorded there.
The source of the virus on board remains unknown.
Standoff in Praia
The MV Hondius remains stationary off the coast of Praia, the capital of Cape Verde, while negotiations continue regarding medical evacuation. Oceanwide Expeditions stated that Dutch authorities have approved the repatriation of sick crew members and the remains of one victim to the Netherlands, but implementation depends on local authorities’ decisions.
The WHO is coordinating efforts between the ship operator and health authorities in South Africa, Cape Verde, and Saint Helena.
Oceanwide Expeditions Response
Oceanwide Expeditions stated that passengers and crew are receiving medical care, and ongoing investigations include further laboratory testing and virus sequencing. The operator stated its priority is to provide medical assistance to the two patients still onboard as quickly as possible.



